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KMID : 1134820160450111571
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Journal of the Korean Society of Food Science and Nutrition
2016 Volume.45 No. 11 p.1571 ~ p.1579
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Effects of Peanut Sprout (Arachis hypogaea L.) Extract on Partial Androgen Deficiency in Aging Males (PADAM)
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Sung Hea-Mi
Wee Ji-Hyang
Jung Hyun-Jung
Kim Yoon-Hee
Moon Joo-Myeng
Jun Woo-Jin
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Abstract
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We investigated the effect of peanut sprout extract (PSE) on andropause symptoms. PSE was evaluated for impotency and benign prostatic hyperplasia via phosphodiesterase (PDE) or 5-alpha reductase Ⅱ inhibition assay. Inhibition of PDE and 5-alpha reductase Ⅱ activities in PSE was significantly higher than that of the non-treated control. To investigate the effects of testosterone levels by PSE, we performed cell media test using TM3 cells. Production of testosterone in TM3 cells was elevated by PSE. These results indicate that PSE was able to alleviate andropause symptoms.
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KEYWORD
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peanut sprout, 5-alpha reductase, testosterone, benign prostatic hyperplasia
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